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Year : 2017  |  Volume : 17  |  Issue : 2  |  Page : 120-127

Demineralized dentin matrix scaffolds for alveolar bone engineering

1 R & D Institute, Korea Tooth Bank, Seoul, Korea
2 Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam; Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea
3 Takamatsu Oral and Maxillofacial Surgery Clinic, Takamatsu, Japan

Correspondence Address:
In-Woong Um
R & D Institute, Korea Tooth Bank, Seoul-In Dental Clinic, 622, Eonju-ro, Gangnam-gu, Seoul 135-832
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jips.jips_62_17

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From the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are presented to emphasize the similarities with autogenous bone. Studies of DDM properties, such as osteoinductive and osteoconductive functions as well as efficacy and safety, which are mandatory for its use as a bone graft substitute, are also presented. The clinical applications of powder, block, and moldable DDM are discussed, along with future developments that can support growth factor and stem cell delivery.

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